MSC therapies hold great potential as an “off-the-shelf” therapeutic product in regenerative medicine and autoimmune disease based on their differentiation ability and immunosuppressive properties. This is because MSCs express less MHC class II protein which makes MSC a potential candidate for “off-the-shelf” cell therapy product and causes a less immune response in the recipient. Furthermore, MSCs secrete various cytokines and growth factors that provide the paracrine effect to stimulate the regeneration of damaged tissue.
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