Cell Secretory

Secretome refer to any tropic factors that secrete by cell in soluble form or membrane-bounded vesicles. One of the valuable tropic factors that have been proved has a therapeutic effect is exosome.

Exosomes are nano-particles in size range of 40–120 nm and contain numerous proteins and genetic material that naturally implicated in cellular communication, cellular structure, tissue repair and regeneration, and metabolism. Hence, these exosomes are potentially used in regenerative medicine as they carrying various bio-information for cell signaling.

It has also been demonstrated that dermal fibroblast secretions contained various protein and small molecules such as collagen I, IV, XII and fibronectin which accelerate wound healing and possess anti-aging properties, which are a wonderful ingredient for cosmetics product.

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